Papers

A Single Mutation in an Enteric Virus Alters Tropism and Sensitivity to Microbiota

Erickson AK, Sutherland DM, Welsh OL, Maples RW, Dermody TS, Pfeiffer JK. 2024.

Murine norovirus mutants adapted to replicate in human cells reveal a post-entry restriction.

Budicini MR, Rodriguez-Irizarry VJ, Maples RW, Pfeiffer JK. J. Virol. 2024 Preprint

Stabilization of Murine Norovirus by Bacteria.

Budicini MR, Pfeiffer JK. mSphere. 2022. Preprint

STING mediates immune responses in the closest living relatives of animals.

Woznica A, Kumar A, Sturge CR, Xing C, King N, Pfeiffer JK. eLife. 2021. Preprint

Tradeoffs for a viral mutant with enhanced replication speed.

Lanahan MR, Maples RW, Pfeiffer JK, Proc Natl Acad Sci U S A 2021 Preprint

Microbiota-independent antiviral effects of antibiotics on poliovirus and coxsackievirus.

Woods Acevedo MA, Pfeiffer JK, Virology 2020 Preprint

Use of a glycan library reveals a new model for enteric virus oligosaccharide binding and virion stabilization.

Lu H, Lehrman MA, Pfeiffer JK, J. Virol. 2019 Preprint

Rapid dissemination and monopolization of viral populations in mice revealed using a panel of barcoded viruses.

McCune BT, Lanahan MR, tenOever BR, Pfeiffer JK, J. Virol. 2019 Preprint

Related enteric viruses have different requirements for host microbiota in mice.

Robinson CM, Woods Acevedo MA, McCune BT, Pfeiffer JK, J. Virol. 2019 Preprint

Bacterial Stabilization of a Panel of Picornaviruses.

Aguilera ER, Nguyen Y, Sasaki J, Pfeiffer JK, mSphere 2019 Preprint

Identification and Characterization of a Poliovirus Capsid Mutant with Enhanced Thermal Stability.

Nguyen Y, Jesudhasan PR, Aguilera ER, Pfeiffer JK, J. Virol. 2019 Preprint

The Antibiotic Neomycin Enhances Coxsackievirus Plaque Formation.

Woods Acevedo MA, Erickson AK, Pfeiffer JK, mSphere 2019 Preprint

Bacteria Facilitate Enteric Virus Co-infection of Mammalian Cells and Promote Genetic Recombination.

Erickson AK, Jesudhasan PR, Mayer MJ, Narbad A, Winter SE, Pfeiffer JK Cell Host Microbe 2018 Preprint

Plaques Formed by Mutagenized Viral Populations Have Elevated Coinfection Frequencies.

Aguilera ER, Erickson AK, Jesudhasan PR, Robinson CM, Pfeiffer JK MBio 2017 Preprint

Sex-dependent intestinal replication of an enteric virus.

Robinson CM, Wang Y, Pfeiffer JK J. Virol. 2017

Emergence of a Large-Plaque Variant in Mice Infected with Coxsackievirus B3.

Wang Y, Pfeiffer JK MBio 2016

Comparison of three neurotropic viruses reveals differences in viral dissemination to the central nervous system.

Luethy LN, Erickson AK, Jesudhasan PR, Ikizler M, Dermody TS, Pfeiffer JK Virology 2015

Spectrum of disease outcomes in mice infected with YFV-17D.

Erickson AK, Pfeiffer JK J. Gen. Virol. 2015

Bacterial lipopolysaccharide binding enhances virion stability and promotes environmental fitness of an enteric virus.

Robinson CM, Jesudhasan PR, Pfeiffer JK Cell Host Microbe 2014

Dynamic viral dissemination in mice infected with yellow fever virus strain 17D.

Erickson AK, Pfeiffer JK J. Virol. 2013

Intestinal microbiota promote enteric virus replication and systemic pathogenesis.

Kuss SK, Best GT, Etheredge CA, Pruijssers AJ, Frierson JM, Hooper LV, Dermody TS, Pfeiffer JK Science 2011

Mechanisms controlling virulence thresholds of mixed viral populations.

Lancaster KZ, Pfeiffer JK J. Virol. 2011

Host-based ribavirin resistance influences hepatitis C virus replication and treatment response.

Ibarra KD, Jain MK, Pfeiffer JK J. Virol. 2011

Limited trafficking of a neurotropic virus through inefficient retrograde axonal transport and the type I interferon response.

Lancaster KZ, Pfeiffer JK PLoS Pathog. 2010

Reduced ribavirin antiviral efficacy via nucleoside transporter-mediated drug resistance.

Ibarra KD, Pfeiffer JK J. Virol. 2009

Multiple host barriers restrict poliovirus trafficking in mice.

Kuss SK, Etheredge CA, Pfeiffer JK PLoS Pathog. 2008